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Positional Distributions of the Tethered Modules in Nitric Oxide Synthase: Monte Carlo Calculations and Pulsed EPR Measurements

The nitric oxide synthase (NOS) enzyme consists of multiple domains connected by flexible random coil tethers. In a catalytic cycle, the NOS domains move within the limits determined by the length and flexibility of the interdomain tethers, and form domain-domain docking complexes. This process repr...

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Detalhes bibliográficos
Publicado no:J Phys Chem A
Main Authors: Astashkin, Andrei V., Li, Jinghui, Zheng, Huayu, Feng, Changjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534783/
https://ncbi.nlm.nih.gov/pubmed/31310526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpca.9b05388
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