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Enhancement of the FMN–heme interdomain electron transfer in neuronal nitric oxide synthase by heat shock protein 90

Purified dimeric human Hsp90α was used to investigate whether Hsp90 affects the FMN–heme interdomain electron transfer (IET), an essential step in nitric oxide synthase (NOS). The IET rate for rat neuronal NOS (nNOS) displayed a noticeable increase upon adding Hsp90 in a dose-saturable manner, and t...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Zheng, Huayu, Li, Jinghui, Feng, Changjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722166/
https://ncbi.nlm.nih.gov/pubmed/32573772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13870
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