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Enhancement of the FMN–heme interdomain electron transfer in neuronal nitric oxide synthase by heat shock protein 90
Purified dimeric human Hsp90α was used to investigate whether Hsp90 affects the FMN–heme interdomain electron transfer (IET), an essential step in nitric oxide synthase (NOS). The IET rate for rat neuronal NOS (nNOS) displayed a noticeable increase upon adding Hsp90 in a dose-saturable manner, and t...
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| Publié dans: | FEBS Lett |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722166/ https://ncbi.nlm.nih.gov/pubmed/32573772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13870 |
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