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Fast randomization of large genomic datasets while preserving alteration counts

Motivation: Studying combinatorial patterns in cancer genomic datasets has recently emerged as a tool for identifying novel cancer driver networks. Approaches have been devised to quantify, for example, the tendency of a set of genes to be mutated in a ‘mutually exclusive’ manner. The significance o...

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Bibliografski detalji
Glavni autori: Gobbi, Andrea, Iorio, Francesco, Dawson, Kevin J., Wedge, David C., Tamborero, David, Alexandrov, Ludmil B., Lopez-Bigas, Nuria, Garnett, Mathew J., Jurman, Giuseppe, Saez-Rodriguez, Julio
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147926/
https://ncbi.nlm.nih.gov/pubmed/25161255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu474
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