Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3

The anti-leukemic activity of the mitochondria-targeting small molecule sodium dichloroacetate (DCA), used alone and in association with the small molecule inhibitor of the p53/MDM2 interaction Nutlin-3, was analyzed in primary B-chronic lymphocytic leukemia (B-CLL) samples (n=22), normal peripheral...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Agnoletto, Chiara, Melloni, Elisabetta, Casciano, Fabio, Rigolin, Gian Matteo, Rimondi, Erika, Celeghini, Claudio, Brunelli, Laura, Cuneo, Antonio, Secchiero, Paola, Zauli, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147328/
https://ncbi.nlm.nih.gov/pubmed/24962518
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados