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Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage
BACKGROUND: The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4147166/ https://ncbi.nlm.nih.gov/pubmed/25149897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-561 |
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