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Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage
BACKGROUND: The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vit...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4147166/ https://ncbi.nlm.nih.gov/pubmed/25149897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-561 |
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