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Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage

BACKGROUND: The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vit...

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Détails bibliographiques
Auteurs principaux: Chen-Roetling, Jing, Cai, Ying, Regan, Raymond F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147166/
https://ncbi.nlm.nih.gov/pubmed/25149897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-561
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