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Making the Most of Clinical Data: Reviewing the Role of Pharmacokinetic-Pharmacodynamic Models of Anti-malarial Drugs

Mechanistic within-host models integrating blood anti-malarial drug concentrations with the parasite-time profile provide a valuable decision tool for determining dosing regimens for anti-malarial treatments, as well as a formative component of population-level drug resistance models. We reviewed pu...

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Main Authors: Simpson, Julie A., Zaloumis, Sophie, DeLivera, Alysha M., Price, Ric N., McCaw, James M
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147051/
https://ncbi.nlm.nih.gov/pubmed/25056904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9647-y
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