Towards optimal design of anti-malarial pharmacokinetic studies

BACKGROUND: Characterization of anti-malarial drug concentration profiles is necessary to optimize dosing, and thereby optimize cure rates and reduce both toxicity and the emergence of resistance. Population pharmacokinetic studies determine the drug concentration time profiles in the target patient...

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Detalhes bibliográficos
Main Authors: Simpson, Julie A, Jamsen, Kris M, Price, Ric N, White, Nicholas J, Lindegardh, Niklas, Tarning, Joel, Duffull, Stephen B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732628/
https://ncbi.nlm.nih.gov/pubmed/19656413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-189
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