ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint

The spindle assembly checkpoint (SAC), which blocks anaphase onset until all chromosomes have bi-oriented, is one of the key self-monitoring systems of the eukaryotic cell cycle for genome stability. The mitotic arrest-deficient protein 1 (Mad1), a critical component of the SAC, is hyperphosphorylat...

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Main Authors: Yang, Chunying, Hao, Jianwei, Kong, Dejuan, Cui, Xiaoli, Zhang, Wei, Wang, Haibo, Guo, Xiaojing, Ma, Shumei, Liu, Xiaodong, Pu, Peiyu, Xu, Bo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146412/
https://ncbi.nlm.nih.gov/pubmed/24728176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu087
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