ONCOLYTIC POLIOVIRUS IMMUNOTHERAPY OF GLIOBLASTOMA

BACKGROUND: With the exception of Burkitt lymphoma, almost all solid cancers are susceptible to infection with poliovirus, due to widespread ectopic expression of the poliovirus receptor, the onco-fetal cell adhesion molecule Necl5/CD155. We engineered a profoundly CNS-incompetent and genetically st...

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Hlavní autoři: Gromeier, Matthias, Dobrikova, Elena, Dobrikov, Mikhail, Brown, Michael, Bryant, Jeffrey, Threatt, Stevie, Boulton, Susan, Carter, Karen, Herndon, James, Desjardins, Annick, Friedman, Henry, Sampson, John, Friedman, Alan, Bigner, Darell
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144618/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.69
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