IDH1 MUTATIONS AS A IMMUNOTHERAPEUTIC TARGET FOR BRAIN TUMORS

BACKGROUND: Immunotherapy promises an exquisitely precise therapeutic approach, and substantial evidence suggests that activated T cells can eradicate large tumors, even within the “immunologically privileged” brain. EGFRvIII and isocitrate dehydrogenase 1 (IDH1) mutations are two of the only consis...

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Detalhes bibliográficos
Main Authors: Archer, Gary E., Reap, Elizabeth, Norberg, Pam, Cui, Xiuyu, Schmittling, Robert, Herndon, James, Chandramohan, Vidya, Riccione, Katherine, Kuan, Chien-Tsun, Yan, Hai, Bigner, Darell D., Sampson, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144614/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.65
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