TRANSCRIPTIONAL PROFILING OF GBM INVASIVE GENES IDENTIFIES EFFECTIVE INHIBITORS OF THE LIM KINASE-COFILIN PATHWAY

BACKGROUND: The malignant astrocytoma is a highly proliferative and invasive neoplasm that infiltrates diffusely into regions of normal brain rendering total surgical resection impossible and effective local radiation therapy difficult. For truly significant advances to be made in the treatment of p...

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Autores principales: Rutka, James, Park, Jun-Bum, Agnihotri, Sameer, Golbourn, Brian, Bertrand, Kelsey, Luck, Amanda, Sabha, Nesrin, Croul, Sidney, Smith, Christian A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144590/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.43
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