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Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion

The aggressive brain tumor glioblastoma (GBM) is characterized by rapid cellular infiltration of brain tissue, raising the possibility that disease progression could potentially be slowed by disrupting the machinery of cell migration. The LIM kinase isoforms LIMK1 and LIMK2 (LIMK1/2) play important...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Chen, Joseph, Ananthanarayanan, Badriprasad, Springer, Kelsey S., Wolf, Kayla J., Sheyman, Sharon M., Tran, Vivien D., Kumar, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942638/
https://ncbi.nlm.nih.gov/pubmed/31641031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1237
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