A role for LIM kinase in cancer invasion

In this study, we show that LIM kinase 1 (LIMK1), a critical regulator of actin dynamics, plays a regulatory role in tumor cell invasion. We found that the level and activity of endogenous LIMK1 is increased in invasive breast and prostate cancer cell lines in comparison with less invasive cells. Ov...

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Detaylı Bibliyografya
Asıl Yazarlar: Yoshioka, Kiyoko, Foletta, Victoria, Bernard, Ora, Itoh, Kazuyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC165861/
https://ncbi.nlm.nih.gov/pubmed/12777619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232344100
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