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Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets
Cofilin is a regulator of actin filament dynamics. We studied whether during platelet activation Rho kinase stimulates LIM kinase (LIMK) leading to subsequent phosphorylation and inactivation of cofilin. Platelet shape change and aggregation/secretion were induced by low and high concentrations of t...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society of Hematology
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895613/ https://ncbi.nlm.nih.gov/pubmed/16219803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-11-4377 |
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