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Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCδ in platelets

Thrombin has been known to cause tyrosine phosphorylation of protein kinase C δ (PKCδ) in platelets, but the molecular mechanisms and function of this tyrosine phosphorylation is not known. In this study, we investigated the signaling pathways used by protease-activated receptors (PARs) to cause tyr...

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Библиографические подробности
Главные авторы: Murugappan, Swaminathan, Shankar, Haripriya, Bhamidipati, Surya, Dorsam, Robert T., Jin, Jianguo, Kunapuli, Satya P.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society of Hematology 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895183/
https://ncbi.nlm.nih.gov/pubmed/15811957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4866
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