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Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCδ in platelets
Thrombin has been known to cause tyrosine phosphorylation of protein kinase C δ (PKCδ) in platelets, but the molecular mechanisms and function of this tyrosine phosphorylation is not known. In this study, we investigated the signaling pathways used by protease-activated receptors (PARs) to cause tyr...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society of Hematology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895183/ https://ncbi.nlm.nih.gov/pubmed/15811957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4866 |
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