Cofilin Oligomer Formation Occurs In Vivo and Is Regulated by Cofilin Phosphorylation

BACKGROUND: ADF/cofilin proteins are key regulators of actin dynamics. Their function is inhibited by LIMK-mediated phosphorylation at Ser-3. Previous in vitro studies have shown that dependent on its concentration, cofilin either depolymerizes F-actin (at low cofilin concentrations) or promotes act...

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Detalhes bibliográficos
Main Authors: Goyal, Pankaj, Pandey, Dharmendra, Brünnert, Daniela, Hammer, Elke, Zygmunt, Marek, Siess, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738525/
https://ncbi.nlm.nih.gov/pubmed/23951242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071769
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