MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.

BACKGROUND: Glioblastomas (GBMs) are highly vascular tumors. Therefore, anti-vascular therapy has been regarded as a promising treatment strategy. Yet, recent results from two double-blind, placebo-controlled phase III trials, (RTOG 0825), and (AVAglio), for first-line treatment of GBM patients did...

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Main Authors: Bjerkvig, Rolf, Fack, Fred, Frezza, Christian, Keunen, Olivier, Stieber, Daniel, Lund-Johansen, Morten, Miletic, Hrvoje, Gottlieb, Eyal, Niclou, Simone P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144581/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.35
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