O10.03 PHYSIOLOGICAL AND BIOLOGICAL RESPONSES OF HUMAN GLIOBLASTOMAS TO BEVACIZUMAB TREATMENT ASSESSED BY METABOLOMIC FLUX ANALYSIS

We have in two different xenograft model systems of human glioblastoma (GBM) that reflect the genotype and phenotype of human GBMs, assessed using 13C6-glucose metabolomic flux analysis, how the tumors adapt to anti-vascular therapy (bevacizumab treatment). A detailed LC-MS analyses of 13C-labeled m...

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Autors principals: Fack, F., Espedal, H., Keunen, O., Golebiewska, A., Obad, N., Zheng, L., Gotlieb, E., Harter, P., Niclou, S., Bjerkvig, R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Oral Presentations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185855/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.84
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