SINGLE CELL DERIVED CLONAL ANALYSIS OF HUMAN GLIOBLASTOMA LINKS FUNCTIONAL AND GENOMIC HETEROGENEITY

BACKGROUND: Glioblastoma (GBM) is a cancer comprised of morphologically, genetically and phenotypically diverse cells. However, an understanding of the functional significance of intratumoral heterogeneity is lacking. METHODS: We devised a method to isolate and functionally profile tumorigenic clone...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Dirks, Peter B., Meyer, Mona, Reimand, Jüri, Lan, Xiaoyang, Head, Renee, Zhu, Xueming, Kushida, Michelle, Bayani, Jane, Pressey, Jessica C., Lionel, Anath, Clarke, Ian D., Cusimano, Michael, Squire, Jeremy, Scherer, Stephen, Bernstein, Mark, Woodin, Melanie A., Bader, Gary D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144519/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.51
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares