Llwytho...

Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers

Large-scale cancer genome sequencing has uncovered thousands of gene mutations, but distinguishing tumor driver genes from functionally neutral passenger mutations is a major challenge. We analyzed 800 cancer genomes of eight types to find single-nucleotide variants (SNVs) that precisely target phos...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Reimand, Jüri, Bader, Gary D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: European Molecular Biology Organization 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564258/
https://ncbi.nlm.nih.gov/pubmed/23340843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.68
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