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Frequent mutations in acetylation and ubiquitination sites suggest novel driver mechanisms of cancer
BACKGROUND: Discovery of cancer drivers is a major goal of cancer research. Driver genes and pathways are often predicted using mutation frequency, assuming that statistically significant recurrence of specific somatic mutations across independent samples indicates their importance in cancer. Howeve...
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| Veröffentlicht in: | Genome Med |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4864925/ https://ncbi.nlm.nih.gov/pubmed/27175787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0311-2 |
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