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Evolutionary Constraint and Disease Associations of Post-Translational Modification Sites in Human Genomes
Interpreting the impact of human genome variation on phenotype is challenging. The functional effect of protein-coding variants is often predicted using sequence conservation and population frequency data, however other factors are likely relevant. We hypothesized that variants in protein post-trans...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303425/ https://ncbi.nlm.nih.gov/pubmed/25611800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004919 |
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