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Evolutionary Constraint and Disease Associations of Post-Translational Modification Sites in Human Genomes
Interpreting the impact of human genome variation on phenotype is challenging. The functional effect of protein-coding variants is often predicted using sequence conservation and population frequency data, however other factors are likely relevant. We hypothesized that variants in protein post-trans...
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| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303425/ https://ncbi.nlm.nih.gov/pubmed/25611800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004919 |
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