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Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers
Large-scale cancer genome sequencing has uncovered thousands of gene mutations, but distinguishing tumor driver genes from functionally neutral passenger mutations is a major challenge. We analyzed 800 cancer genomes of eight types to find single-nucleotide variants (SNVs) that precisely target phos...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
European Molecular Biology Organization
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564258/ https://ncbi.nlm.nih.gov/pubmed/23340843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.68 |
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