DISTINCT COPY NUMBER ALTERATIONS AND INCIDENCE OF CHROMOTHRIPSIS ASSOCIATED WITH GRADE AND PROGNOSIS IN IDH MUTANT AND WILD-TYPE GLIOMAS

BACKGROUND: Both IDH mutated (IDHmut) and wild-type (IDHwt) lower grade gliomas can progress to GBM. However, a detailed study of alterations associated with progression of these molecularly distinct tumor types has not been described. Here we perform an analysis of copy number alterations (CNA) acr...

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Main Authors: Colman, Howard, Cohen, Adam, Aldape, Ken, Sato, Mariko, Mason, Clint, Diefes, Kristin, Heathcock, Lindsey, Abegglen, Lisa, Shrieve, Dennis, Couldwell, William, Schiffman, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144485/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.20
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