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Regression hidden Markov modeling reveals heterogeneous gene expression regulation: a case study in mouse embryonic stem cells

BACKGROUND: Studies have shown the strong association between histone modification levels and gene expression levels. The detailed relationships between the two can vary substantially due to differential regulation, and hence a simple regression model may not be adequate. We apply a regression hidde...

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Autori principali: Lee, Yeonok, Ghosh, Debashis, Zhang, Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144088/
https://ncbi.nlm.nih.gov/pubmed/24884369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-360
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