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Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model

BACKGROUND: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic patterns associated with developmental stages and diseases. However, previous studies have been mostly limited to focal epigenet...

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Detalhes bibliográficos
Main Authors: Larson, Jessica L, Yuan, Guo-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992069/
https://ncbi.nlm.nih.gov/pubmed/21073706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-557
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