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Epigenetic change detection and pattern recognition via Bayesian hierarchical hidden Markov models

Epigenetics is the study of changes to the genome that can switch genes on or off and determine which proteins are transcribed without altering the DNA sequence. Recently, epigenetic changes have been linked to the development and progression of disease such as psychiatric disorders. High-throughput...

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Bibliographic Details
Main Authors: Wang, Xinlei, Zang, Miao, Xiao, Guanghua
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009397/
https://ncbi.nlm.nih.gov/pubmed/23097332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5658
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