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Epigenetic change detection and pattern recognition via Bayesian hierarchical hidden Markov models

Epigenetics is the study of changes to the genome that can switch genes on or off and determine which proteins are transcribed without altering the DNA sequence. Recently, epigenetic changes have been linked to the development and progression of disease such as psychiatric disorders. High-throughput...

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Hlavní autoři: Wang, Xinlei, Zang, Miao, Xiao, Guanghua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009397/
https://ncbi.nlm.nih.gov/pubmed/23097332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5658
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