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Analyzing Single-Molecule Protein Transportation Experiments via Hierarchical Hidden Markov Models

To maintain proper cellular functions, over 50% of proteins encoded in the genome need to be transported to cellular membranes. The molecular mechanism behind such a process, often referred to as protein targeting, is not well understood. Single-molecule experiments are designed to unveil the detail...

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Detalhes bibliográficos
Publicado no:J Am Stat Assoc
Main Authors: Chen, Yang, Shen, Kuang, Shan, Shu-Ou, Kou, S. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606165/
https://ncbi.nlm.nih.gov/pubmed/28943680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2016.1140050
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