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Epigenetic change detection and pattern recognition via Bayesian hierarchical hidden Markov models

Epigenetics is the study of changes to the genome that can switch genes on or off and determine which proteins are transcribed without altering the DNA sequence. Recently, epigenetic changes have been linked to the development and progression of disease such as psychiatric disorders. High-throughput...

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Main Authors: Wang, Xinlei, Zang, Miao, Xiao, Guanghua
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009397/
https://ncbi.nlm.nih.gov/pubmed/23097332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5658
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