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An extended model for culture-dependent heterogenous gene expression and proliferation dynamics in mouse embryonic stem cells

During development, pluripotency is a transient state describing a cell’s ability to give rise to all three germ layers and germline. Recent studies have shown that, in vitro, pluripotency is highly dynamic: exogenous stimuli provided to cultures of mouse embryonic stem cells, isolated from pre-impl...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Godwin, Simon, Ward, Daniel, Pedone, Elisa, Homer, Martin, Fletcher, Alexander G., Marucci, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543144/
https://ncbi.nlm.nih.gov/pubmed/28794899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0020-5
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