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Positive and Negative Phosphorylation Regulates RIP1 and RIP3-Induced Programmed Necrosis
Programmed necrosis or necroptosis is controlled by the action of two serine/threonine kinases, receptor interacting protein kinase 1 (RIP1) and RIP3. The phosphorylation of RIP1 and RIP3 is critical for assembly of the necrosome, an amyloid-like complex that initiates transmission of the pro-necrot...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143978/ https://ncbi.nlm.nih.gov/pubmed/24059293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130860 |
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