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Positive and Negative Phosphorylation Regulates RIP1 and RIP3-Induced Programmed Necrosis

Programmed necrosis or necroptosis is controlled by the action of two serine/threonine kinases, receptor interacting protein kinase 1 (RIP1) and RIP3. The phosphorylation of RIP1 and RIP3 is critical for assembly of the necrosome, an amyloid-like complex that initiates transmission of the pro-necrot...

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Hlavní autoři: McQuade, Thomas, Cho, YoungSik, Chan, Francis Ka-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143978/
https://ncbi.nlm.nih.gov/pubmed/24059293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130860
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