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RIP1-Dependent and Independent Effects of Necrostatin-1 in Necrosis and T Cell Activation

BACKGROUND: Programmed necrosis/necroptosis is an emerging form of cell death that plays important roles in mammalian development and the immune system. The pro-necrotic kinases in the receptor interacting protein (RIP) family are crucial mediators of programmed necrosis. Recent advances in necrosis...

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Detalhes bibliográficos
Main Authors: Cho, YoungSik, McQuade, Thomas, Zhang, Haibing, Zhang, Jianke, Chan, Francis Ka-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154273/
https://ncbi.nlm.nih.gov/pubmed/21853090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023209
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