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Evaluation of gene-based association tests for analyzing rare variants using Genetic Analysis Workshop 18 data

The focus of our work is to evaluate several recently developed pooled association tests for rare variants and assess the impact of different gene annotation methods and binning strategies on the analyses of rare variants under Genetic Analysis Workshop 18 real and simulated data settings. We consid...

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Detalhes bibliográficos
Main Authors: Derkach, Andriy, Lawless , Jerry F, Merico, Daniele, Paterson, Andrew D, Sun, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143759/
https://ncbi.nlm.nih.gov/pubmed/25519417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S9
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