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Evaluation of gene-based association tests for analyzing rare variants using Genetic Analysis Workshop 18 data

The focus of our work is to evaluate several recently developed pooled association tests for rare variants and assess the impact of different gene annotation methods and binning strategies on the analyses of rare variants under Genetic Analysis Workshop 18 real and simulated data settings. We consid...

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Bibliografiske detaljer
Main Authors: Derkach, Andriy, Lawless , Jerry F, Merico, Daniele, Paterson, Andrew D, Sun, Lei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143759/
https://ncbi.nlm.nih.gov/pubmed/25519417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S9
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