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Mixed-effects models for joint modeling of sequence data in longitudinal studies

In this paper, we propose a novel mixed-effects model for longitudinal changes of systolic blood pressure (SBP) over time that can estimate the joint effect of multiple sequence variants on SBP after accounting for familial correlation and the time dependencies within individuals. First we carried o...

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Autori principali: Wu, Yan Yan, Briollais, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143749/
https://ncbi.nlm.nih.gov/pubmed/25519347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S92
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