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Mixed-effects models for joint modeling of sequence data in longitudinal studies

In this paper, we propose a novel mixed-effects model for longitudinal changes of systolic blood pressure (SBP) over time that can estimate the joint effect of multiple sequence variants on SBP after accounting for familial correlation and the time dependencies within individuals. First we carried o...

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Autors principals: Wu, Yan Yan, Briollais, Laurent
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143749/
https://ncbi.nlm.nih.gov/pubmed/25519347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S92
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