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Mixed-effects models for joint modeling of sequence data in longitudinal studies

In this paper, we propose a novel mixed-effects model for longitudinal changes of systolic blood pressure (SBP) over time that can estimate the joint effect of multiple sequence variants on SBP after accounting for familial correlation and the time dependencies within individuals. First we carried o...

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Detalhes bibliográficos
Main Authors: Wu, Yan Yan, Briollais, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143749/
https://ncbi.nlm.nih.gov/pubmed/25519347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S92
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