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A comparison of whole genome sequencing with exome sequencing for family-based association studies

As the cost of DNA sequencing decreases, association studies based on whole genome sequencing are now becoming feasible. It is still unclear, however, how much more we could gain from whole genome sequencing compared to exome sequencing, which has been widely used to study a variety of diseases. In...

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Hlavní autoři: Lacey, Sean, Chung, Jae Yoon, Lin, Honghuang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143706/
https://ncbi.nlm.nih.gov/pubmed/25519383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S38
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