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A comparison of whole genome sequencing with exome sequencing for family-based association studies

As the cost of DNA sequencing decreases, association studies based on whole genome sequencing are now becoming feasible. It is still unclear, however, how much more we could gain from whole genome sequencing compared to exome sequencing, which has been widely used to study a variety of diseases. In...

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Detalhes bibliográficos
Main Authors: Lacey, Sean, Chung, Jae Yoon, Lin, Honghuang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143706/
https://ncbi.nlm.nih.gov/pubmed/25519383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S38
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