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Screening the human exome: a comparison of whole genome and whole transcriptome sequencing
BACKGROUND: There is considerable interest in the development of methods to efficiently identify all coding variants present in large sample sets of humans. There are three approaches possible: whole-genome sequencing, whole-exome sequencing using exon capture methods, and RNA-Seq. While whole-genom...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898068/ https://ncbi.nlm.nih.gov/pubmed/20598109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-5-r57 |
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