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Adenosine A(1) Receptors in Mouse Pontine Reticular Formation Modulate Nociception Only in the Presence of Systemic Leptin

Human obesity is associated with increased leptin levels and pain, but the specific brain regions and neurochemical mechanisms underlying this association remain poorly understood. This study used adult male C57BL/6J (B6, n = 14) mice and leptin-deficient, obese B6.Cg-Lep(ob)/J (obese, n = 10) mice...

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Bibliographic Details
Main Authors: Watson, Sarah L., Watson, Christopher J., Baghdoyan, Helen A., Lydic, Ralph
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143377/
https://ncbi.nlm.nih.gov/pubmed/24976513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.06.025
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