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Adenosine A(1) Receptors in Mouse Pontine Reticular Formation Modulate Nociception Only in the Presence of Systemic Leptin

Human obesity is associated with increased leptin levels and pain, but the specific brain regions and neurochemical mechanisms underlying this association remain poorly understood. This study used adult male C57BL/6J (B6, n = 14) mice and leptin-deficient, obese B6.Cg-Lep(ob)/J (obese, n = 10) mice...

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Detalhes bibliográficos
Main Authors: Watson, Sarah L., Watson, Christopher J., Baghdoyan, Helen A., Lydic, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143377/
https://ncbi.nlm.nih.gov/pubmed/24976513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.06.025
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