An interferon-beta promoter reporter assay for high throughput identification of compounds against multiple RNA viruses

Virus infection of host cells is sensed by innate pattern recognition receptors (PRRs) and induces production of type I interferons (IFNs) and other inflammatory cytokines. These cytokines orchestrate the elimination of the viruses but are occasionally detrimental to the hosts. The outcomes and path...

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Autores principales: Guo, Fang, Zhao, Xuesen, Gill, Tina, Zhou, Yan, Campagna, Matthew, Wang, Lijuan, Liu, Fei, Zhang, Pinghu, DiPaolo, Laura, Du, Yanming, Xu, Xiaodong, Jiang, Dong, Wei, Lai, Cuconati, Andrea, Block, Timothy M., Guo, Ju-Tao, Chang, Jinhong
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier B.V. 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143146/
https://ncbi.nlm.nih.gov/pubmed/24792753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.04.010
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