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Interferon induction of IFITM proteins promotes infection by human coronavirus OC43

IFNs are a family of cytokines that are essential for the antiviral response in vertebrates. Not surprisingly, viruses have adapted to encode virulence factors to cope with the IFN response. Intriguingly, we show here that all three types of interferons, IFN-α, IFN-γ, and IFN-λ, efficiently promote...

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Detalhes bibliográficos
Main Authors: Zhao, Xuesen, Guo, Fang, Liu, Fei, Cuconati, Andrea, Chang, Jinhong, Block, Timothy M., Guo, Ju-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020042/
https://ncbi.nlm.nih.gov/pubmed/24753610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320856111
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