Identification of Residues Controlling Restriction versus Enhancing Activities of IFITM Proteins on Entry of Human Coronaviruses

Interferon-induced transmembrane proteins (IFITMs) are restriction factors that inhibit the infectious entry of many enveloped RNA viruses. However, we demonstrated previously that human IFITM2 and IFITM3 are essential host factors facilitating the entry of human coronavirus (HCoV) OC43. In a contin...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Zhao, Xuesen, Sehgal, Mohit, Hou, Zhifei, Cheng, Junjun, Shu, Sainan, Wu, Shuo, Guo, Fang, Le Marchand, Sylvain J., Lin, Hanxin, Chang, Jinhong, Guo, Ju-Tao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827390/
https://ncbi.nlm.nih.gov/pubmed/29263263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01535-17
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