Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma

To understand the relationships between the non-GCIMP glioblastoma (GBM) subgroups, we performed mathematical modeling to predict the temporal sequence of driver events during tumorigenesis. The most common order of evolutionary events is 1) chromosome (chr) 7 gain and chr10 loss, followed by 2) CDK...

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Autori principali: Ozawa, Tatsuya, Riester, Markus, Cheng, Yu-Kang, Huse, Jason T, Squatrito, Massimo, Helmy, Karim, Charles, Nikki, Michor, Franziska, Holland, Eric C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143139/
https://ncbi.nlm.nih.gov/pubmed/25117714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.06.005
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